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1.
Journal of Contemporary Studies in Epidemiology and Public Health ; 3(1), 2022.
Artículo en Inglés | ProQuest Central | ID: covidwho-2081461

RESUMEN

Introduction and Objectives: Man-made disasters can be grouped as technology and violence origin such disasters occur as a result of conscious or unconscious mistakes where chemical, biological, radiological, and nuclear threats are used. It has become significant for hospitals to prepare a plan, which includes information and practical actions, including all situations that require urgency and actions to be taken in emergencies that may occur in workplaces. Coronaviruses are a diverse group of viruses that infect many different animals and can cause mild to severe respiratory infections in humans. Two highly pathogenic coronaviruses of zoonotic origin, the severe acute respiratory syndrome coronavirus (SARS-CoV) and the Middle East respiratory syndrome coronavirus (MERS-CoV), emerged in humans in 2002 and 2012, respectively. At the end of 2019, the emergence of a new coronavirus, SARS-CoV-2, in the Chinese city of Wuhan caused an unusual viral pneumonia epidemic. In this study, hospital emergency management plan is examined to the currently effective pandemic element of COVID-19 disease. Methods: It reviews the current situation and recommended actions to improve the preparedness of hospitals in five critical hospital roles during disasters: executing planning and coordination, maintaining disaster capacity, training and disaster drills with the broader health and public safety communities, protection hospital and staff, and surveillance as showing. In this context, coranavirus (SARS-CoV-2) COVID-19 hospital disaster emergency plan system model has been tried to be created. While creating the system method, it proposes a model of how the primary diagnosis and intermediate treatments will be handled in the risk method for the emergency room cases and the clinic, by handling confirmed and suspected cases through both the healthcare personnel and the medical supply system. Results and Conclusions: As a result, the hospital emergency management plan can ease the emergency department workload, protect healthcare personnel, and control cross infection during the COVID-19 outbreak. Each hospital needs to create an emergency plan suitable for its own conditions. Hospitals can take interim measures, including online consultation, zoning, and epidemic priority to relieve pressure on clinical trials, reduce cross-infection, and strengthen protection of high-risk personnel.

2.
Journal of Clinical and Experimental Investigations ; 13(4), 2022.
Artículo en Inglés | ProQuest Central | ID: covidwho-2081460

RESUMEN

Background: Nowadays, people have faced with a pandemic called COVID-19. The reliable detection of the virus is important to prevent transmission of the virus. RT-PCR is a gold standard method for the diagnosis of the disease used at all over the world. The highest number of sample size (1,461,258 patient sample) and differing results are reported with our study regarding the PCR positivity rates. Method/Study Design: The study was aimed to evaluate the positivity and negativity of the patients with RT-PCR from all the samples studied between March 25, 2020 and March 25, 2021, when the pandemic was declared and started to be seen in Turkey, and to investigate its contribution to the total test capacity of our country. Results/Conclusions: 1,461,258 patient is observed, and this frequency male is 58% and female is 42% of the population. The maximum number of admissions is noticed during the Autumn-2020 involved age ranged from 25 to 35. 14.6% positive result is got while the 85.4% negative result is observed. When the age distribution of COVID-19 (+) patients is evaluated, COVID-19 (+) rate is highest in the 6-15 age range, followed by the 66-75 age range and the highest COVID-19 (+) rate are November and October, respectively. Additionally, the highest COVID-19 (+) rate is in Autumn. According to the test results, it was determined that 7.5% of the male participants were COVID-19 (+) and 7.1% of the female participants were COVID-19 (+).

3.
J Med Virol ; 94(3): 1009-1019, 2022 03.
Artículo en Inglés | MEDLINE | ID: covidwho-1718367

RESUMEN

Rapid and reliable detection of severe acute respiratory syndrome coronavirus 2 mutations are significant to control the contagion and spread rate of the virus. We aimed to evaluate the N501Y mutation rate in randomly chosen positive patients with the polymerase chain reaction (PCR). The evaluation and analysis of the data with a retrospective approach in cases with mutations, in terms of public health, will contribute to the literature on the global pandemic that affects our society. Public health authorities will take the necessary precautions and evaluate the current situation. The N501Y mutation was detected in patients with positive Covid-19 PCR test results. The positive samples were examined based on the 6-carboxy-fluorescein (FAM) channel in reverse transcription PCR (RT-PCR) quantitation cycle (Cq) values as low Cq (<25), medium Cq (25-32), and high Cq (32-38) groups. In the study, 2757 (19.7%) of 13 972 cases were detected as mutation suspects and 159 (5.8%) of them were found to have mutations. The ages of the cases with mutations ranged from 1 to 88 years (mean age of 40.99 ± 17.55). 49.7% (n = 79) of the cases with mutations were male, and 50.3% (n = 80) were female. When the RT-PCR-Cq results were examined, it was seen that it varied between 11.3 and 35.03, with an average of 20.75 ± 3.32.


Asunto(s)
COVID-19 , SARS-CoV-2 , Glicoproteína de la Espiga del Coronavirus , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Prueba de Ácido Nucleico para COVID-19 , Niño , Preescolar , Femenino , Humanos , Lactante , Masculino , Persona de Mediana Edad , Mutación , Estudios Retrospectivos , SARS-CoV-2/genética , Glicoproteína de la Espiga del Coronavirus/genética , Adulto Joven
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